Patterned by adhesion

Patterned by adhesion

Patterned by adhesion laborate tissue patterns are formed by two cell types with complementary adhesion molecules, as revealed by Sujin Bao and Ross Cagan (Washington University, St. Louis, MO). Favored heterophilic attractions between the two adhesion molecules, they show, pattern the fly eye. Patterning has often taken a back seat to fate determination in cell biology studies. “We’ve spent bu...

Nanometer-scale patterned surfaces for control of cell adhesion.

A novel cell-adhesion surface, controlled by nanometer-scale topography and chemical patterning, was developed using semiconductor fabrication methods and the formation of self-assembled monolayers. The patterned surface had a sharp contrast between the adsorption and non-adsorption of proteins and cells, and the contrast could be maintained for more than 10 days. The patterning method could ea...

Gecko Adhesion on Wet and Dry Patterned Substrates

Perhaps one of the most astounding characteristics of the gecko adhesive system is its versatility. Geckos can locomote across complex substrates in a variety of conditions with apparent ease. In contrast, many of our synthetic pressure sensitive adhesives fail on substrates that are dirty, wet or rough. Although many studies have investigated the effect of environmental challenges on performan...

Enhanced Cell Adhesion and Alignment on Micro-Wavy Patterned Surfaces

Various micropatterns have been fabricated and used to regulate cell adhesion, morphology and function. Micropatterns created by standard photolithography process are usually rectangular channels with sharp corners (microgrooves) which provide limited control over cells and are not favorable for cell-cell interaction and communication. This paper proposes a new micropattern with smooth wavy sur...

Discriminatory Bio-Adhesion Over Nano-Patterned Polymer Brushes